As we know that the heart attack usually occurs because of the clotting of the blood in the coronary artery, aorta or in the heart vacuoles.
Studies in the Washington have shown that after the heart attack, heart remains no more able to replace dead cells. The presence of dead cells in the heart results in reduced chances of the heart transplant in the body of that patient, it also decreases the chances of cell therapy which transplants the heart cells in the patient’s heart.
In most of the cases, the transplant of heart cells has not shown good results, the heart cells in those cases were not grafted well and were not able to recover soon. The main reason for the poor result of the engraftment of heart cell is the poor quality of the transplanted heart cells. Most of the transplanted heart cells are made from stem cells but the heart cells vary in their quality.
Kyoto University, Dr. Shunsuke Funakoshi, was the first author which made a study on the transplantation of heart cells and concluded that the cells of different maturation will be mixed and transplanted together.
Amid the exploration, Funakoshi took prompted pluripotent stem (iPS) cells that were reconstructed from skin cells and made them into heart cells. Heart cells separated from iPS cells viably experience all phases of improvement.
Presently, over a billion cells are required for human heart cell treatments. Knowing which cells are best for the treatment ought to enhance tolerant result, as well as decrease the quantity of cells required, which assist would diminish both the season of the readiness and intrusiveness of the strategy.