According to a new study, a simple blood sample may help identify signs of multiple sclerosis, the disease of the brain and spinal cord. The modern procedure for detection of the disease needs the invasive, often painful, process of accumulating fluid from the brain and spine. The analysis classified two genetic biomarker compounds, which have been associated with multiple sclerosis.
The compounds, sphingosine and dihydrosphingosine, were determined to be at significantly lower concentrations in blood samples from people living with multiple sclerosis. As well as suggesting a diagnostic tool to identify MS, the findings will aid the examination of the use of the compounds in the disease and help potential new drug development.
The study, issued in the journal Analytical Methods, the researchers from the University of Huddersfield in England practised advanced mass spectrometry techniques. “Sphingosine and dihydrosphingosine have been earlier observed to be at lower concentrations in the brain tissue of victims with multiple sclerosis. The discovery of these sphingolipids in blood plasma enables the non-invasive monitoring of these and related compounds,” Sean Ward, from the University of Huddersfield said. Read here fruits and veggies can help reduce symptoms of multiple sclerosis
In MS, the immune system hits the protective case that coats nerve fibres and generates communication difficulties between the brain and the rest of your body. Eventually, the disease can cause the nerves themselves to decay or become lastingly damaged. Critical MS may lead some people to lose the capacity to walk independently or at all.