A heavy period when coupled with painful cramps could turn your week into disaster. Dealing with long-lasting heavy periods is uncomfortable which is why researchers have come up with a new solution for the issue. A team of scientists in the UK at the University of Edinburgh has successfully identified the key factor that is responsible for heavy bleeding. A protein named HIF-1 is why women suffer from prolonged and heavy periods.
The study revolved around the lining of the womb which is termed as “Endometrium”. Women usually shed this layer during the onset of menstruation. This leaves a surface similar to a wound which must heal in order to avoid the loss of blood. The team observed that a lower level of oxygen which is termed as hypoxia leads to the production of HIF-1. This, in turn, helps in repairing the lining of a woman’s womb.
Women who experience heavy bleeding usually have a reduced level of this protein in comparison with the ones that have normal blood loss. The findings of this research could provide hope for the women suffering from this issue. HIF-1 is responsible for faster tissue repair and a reduced amount of blood loss.
Jackie Maybin, a researcher at the MRC Centre for Reproductive Health from the University of Edinburgh stated that an increased level of HIF-1 during menstruation requires a low level of oxygen to be present in the womb. This, in turn, shall optimize the level of tissue repair seen in the womb. The findings of this study have been published in the journal named Nature Communications.
The HIF-1 can be introduced into the bloodstreams of those affected by this condition as a hormonal therapy. More than 30 percent of the visits to gynecologist every year is about complaints related to heavy bleeding. Heavy bleeding diagnosis can be a subjective topic but in medical terms, it is any menstrual cycle that is more than 80ml.
Heavy bleeding could lead to anemia which is when the RBCs do not carry enough oxygen required for the body. Severe menstrual could also result in abdominal pain which in turn disrupts your daily life cycle. Currehormone-based based therapies are the only option for heavy bleeding which often hampers the fertility. The HIF-1 needs to be studied further to develop a therapy that would have no consequence on the fertility of a woman.