Intranasal insulin may be a potential treatment for Alzheimer's

Scientists might have found a potential treatment to Alzheimer’s and many forms of dementia. A new study says that insulin – a hormone secreted by the pancreas to keep a check on sugar level in the body can be used to treat the diseases that affect our cognitive functions. Insulin goes high up in the nasal activity and helps in improving affected areas of brain as well as memory, say study authors.

“Before this study, there was very little evidence of how insulin gets into the brain and where it goes,” said William Banks, University of Washington (UW) professor of internal medicine and geriatrics.”We showed that insulin goes to areas where we hoped it would go,” said Bank.

In the study, researchers found that insulin when injected intranasally into the body, does not go into the blood stream instead its repeated dosage increases insulin’s efficiency to improve cognitive functions and memory.

Researchers conducted the study over mouse aged between 8 to 12 months. All the participant mouse had severe learning and memory problems, researchers said. The study authors in the first round conducted object recognition test that checks mouse’s natural curiosity for new things. In the second round, mouse were given intranasal insulin and they were subjected to the same test. Researchers noted that the mouse in the second round remembered the objects that were shown to them earlier. Thus, they concluded that insulin might aid to memory and cognitive functions of the brain.

Since, diseases like Alzheimer’s and dementia have been gripping people at a much faster rate in twenty-first century, also doctors have no accurate medicine to prevent such diseases. In such a scenario, the study has given a new ray of hope for the victims of Alzheimer’s. However, more study and several trials are needed to confirm the findings.

The study appeared in the journal Alzheimer’s Disease.

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