Do you find yourself in obese category but not in diabetic? Here is the sigh of relief as researchers have found that a drug used to treat diabetes can help people in cutting weight who are not diabetic. In addition, the reduction in weight is persistent even after a person stops consuming the drug.
Drug liraglutide has shown promising results and nearly 63 percent of patients who consumed the drug for 56 weeks continuously saw 5 percent reduction in body weight while 27 percent of the placebo group lost similar weight.
Lead study author Dr Xavier Pi-Sunyer, a professor of medicine at Columbia University Medical Centre said the drug has been very effective in cutting down weight by a significant amount. In addition, it has given a new alternative for the patients who find it difficult to lose weight or have trouble in maintaining the weight loss once they lose weight.
While explaining Pi-Sunyer said that liraglutide is a drug made by Nono Nordisk company and is alternative for naturally occurring hormone called glucagon-like peptide 1. Peptide 1 is released in the intestine and its main function is to reduce hunger, increase satiety, also it slows down the rate at which the stomach release its food content into the small intestine. Liraglutide was approved by the US Food and Drug Administration for treating diabetes back in December 2014.
For the study, Pi-Sunyer involved 3,731 participants (men and women). All the participants had Body Mass Index (BMI) greater than 30, however, volunteers with high blood pressure and high cholesterol level with BMI 27 and greater also were included for the study. Nearly 2,500 participants received 3.0 milligrams of liraglutide drug daily and about 1,200 were given the placebo injections. All the participants had counselling session on changing their lifestyle. The entire process was repeated for 56 weeks.
After analysing the data, the study authors found that participants who were given liraglutide lost an average of 8.3 kg while participants on placebo shots lost 2.9 kg. It was also noted that 33 percent patients on liraglutide lost nearly 10 percent of their while only 11 percent patients on placebo shots reported reduction in similar amount of weight.
While the drug has shown positive results, it has some side effects too. Pi-Sunyer said that the patients who underwent the treatment suffered nausea and diarrhoea. Also, they had increased of problems related with the gallbladder.
Moreover, the treatment is very costly as of now and its drills almost $1000 every month from your pocket. Scientists are looking forward in making the treatment cheaper so that it becomes feasible for everyone to undergo the treatment. Since, obesity is one of the most common disease in the world and with obesity comes the fear of several other diseases like diabetes, cardiovascular diseases including heart attack, etc. Thus, it is always better to keep the body in tone and live an obesity free life.
The study was published in the New England Journal of Medicine.Tags: cardiovascular, diabetes, Obesity, weight, weight loss